Cannabinoid variant: THCV

1 Jun 2022 | CBD


THCV or tetrahydrocannabivarin is a cannabinoid that offers other effects than the now known THC and CBD.

Its molecular formula being quite close to its cousin THC, the two accomplices will bind to the CB1 receptors of our nervous system. Combined, they provide effects often found in cannabis sativa strains.

The psychoactive effect of THCV

It acts much like mango by facilitating the access of THC to CB1 receptors. It increases the euphoric sensation that THC gives during half of its action time, which brings the feeling of rapid rise and fall when it is metabolized. It is found in the Sativa variety because it provides a more energetic and euphoric high than varieties with low THCV levels. It would be at the origin of the slower “foncedalle” provided by these varieties. It also blocks two notorious negative effects of THC: immediate memory loss and increased blood flow.

A promising medicinal future

Research is mainly focused on the medicinal effects of THCV. In addition to a treatment against obesity, it would help regulate insulin and blood sugar levels for diabetics. The GW Pharmaceuticals laboratories have already started treatments against obesity based on cannabis with a high dose of THCV. The laboratory also markets anti-inflammatory and anticonvulsant treatments with these varieties.

Add to that many interesting avenues such as the reduction of anxiety attacks due to post-traumatic stress syndromes. Trials are also underway for treatments for Alzeihemer’s and Parkinson’s disease, in particular to reduce tremors. Still uncertain, it would reduce psychotic disorders causing the onset of schizophrenia. Some researchers see it as a stimulant of bone development, which could be effective in treatments against osteoporosis

Scientists are now looking to isolate THCV from its cousin THC. Patients could thus obtain almost similar treatments, but without psychoactive effects.